University of California Davis
University of Cincinnati Medical Center
University of Massachusetts Medical School
University of Michigan Medical School
Vanderbilt University School of Medicine
Protocols & Methods
Reagents & Resources
Tissues & Samples
Conditions of Use
Data Usage Policy
Tracers in Metabolic Research
Isotope Tracers in Metabolic Research: 3-Part Webinar Series
Energy Expenditure Analysis
CalR: Indirect Calorimetry Analysis
Guidelines & Policies
New comment to be added:
Influence of Myo KO mutation on metabolic phenotype and energy balance
The objective of this study is to determine if knocking out myoglobin influences
substrate oxidation (respiratory exchange ratio) and other metabolic phenotypes
in high-fat fed, cold-challenged mice.
Male & female MyoKO and litter mate controls will have their baseline energy
expenditure assessed by CLAMS at 5 weeks of age. Animals will be placed on
high-fat (HFD) diet at 6 weeks After 5 weeks on diet (age= 11 w) and 12 weeks on
diet (age=17 w) energy expenditure will be reassessed. Energy expenditure will
be assesses at 10 and 22°C followed by body composition analysis by DEXA.
week(s) post-natal (w)
DOWNLOAD ALL DATA (.csv)
Curation Info (# flags)
Name / Abbreviation
Experimental Factor: Experimental Group
This animal belongs to the control group for the experiment.
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor: Mouse Diet
Teklad - 08511
45% Fat Kcal Diet (ISP) -- The mid-fat diet in a series of diets with isolated soy protein, 10, 45, or 60% kcal from fat, with ~43% of the total carbohydrate from sucrose, and equivalent vitamin and mineral levels adjusted on an energy basis....
Teklad - 2918
Harlan-Teklad 2918 (Irradiated) 18.6% protein (Calories : 24% protein, 18% Fat, 58% Carbohydrate) Ingredients—Ground wheat, ground corn, wheat middlings, dehulled soybean meal, corn gluten meal, soybean oil, calcium carbonate, brewers dried yeast,...
Experimental Factor (Units)
Environmental Temperature (°C) (°C)
Total Time on Diet (wk)
Add / Edit
oxygen consumption (Light Period)
fat body mass
fat body mass
lean body mass
lean body mass
respiratory exchange ratio (Light Period)
bone mineral density
bone mineral content
fat tissue, %
% body fat
heat (Light Period)
oxygen consumption (Dark Period)
carbon dioxide production Light Period
carbon dioxide production Dark Period
respiratory exchange ratio (Dark Period)
heat (Dark Period)
carbon dioxide production
respiratory exchange ratio
energy intake (Light Period)
food intake - light
food intake (Dark Period)
food intake - dark
energy intake (avg 24 hr)
energy intake avg 24
energy intake (Ligth Period)
energy intake -light
energy intake (Dark Period)
energy intake - dark
Activity 24h (total x-axis)
Activity 24h total x
Activity 24h (x-ambulatory)
Activity 24h (x-amb)
Activity 24h (total vertical z-axis)
Activity 24h total z
total tissue mass
heat - 24h
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Financial support for this work was provided by the NIDDK Mouse Metabolic Phenotyping Centers (National MMPC, RRID:SCR_008997,
) under the MICROMouse Program, grants DK076169.
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