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Experiment

Effects of Inulin on high fat diet mediated obesity and gut permeability
Summary Data Summary
Investigator Raybould, Helen
Description This experiment examines the effect of inulin (a dietary fiber), on intestinal
and metabolic function. Mice were fed either a custom low or high fat diets
formulated with cellulose with or without inulin (HF (Research Diets #D08091803B
- 45% kcal fat) (Research Diets #D08091803B - 45% kcal fat) or Research Diets
#D12450J (Research Diets #D12450J - 10% kcal fat)) diet for 6 weeks. At
termination, intestinal sections were collected for gut permeability testing.
Status Completed
Public Release 2/20/2021
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals24
Experimental Conditions5
Catalog Items2
Curation Info (# flags)1
Phenotype Assays2
Phenotype Measurements94
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
24
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Research Diets - D08091803B
Custom high fat diet (45% kcal) with cellulose (20% kcal protein; 35% kcal carbohydrates; 45% kcal fat); energy density = 4.7 kcal/g
 Research Diets - D12450J
Rodent Diet with 10% fat, 70% carbohydrate, 20% protein
 Research Diets - D17041404
Custom low fat (10% kcal) diet with inulin and cellulose (20% kcal protein; 70% kcal carbohydrates; 10% kcal fat); energy density = 3.7 kcal/g
 Research Diets - D17041405
Custom high fat diet (45% kcal) with inulin and cellulose (20% kcal protein; 35% kcal carbohydrates; 45% kcal fat); energy density = 4.6 kcal/g

Experimental Factor: Tissue Source

 colon
colon
 ileum
ileum



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