mmpc-logo
twitter-logo @NationalMMPC
| Create Account | login
Experiment

Effect of Monobutyrin on Intestinal Permeability
Summary Data Summary
Investigator Raybould, Helen
Description This experiment examines the effect of the SCFA analog, monobutyrin, on the
intestinal and metabolic function. Mice were fed either a custom HF (Research
Diets #D08091803B - 45% kcal fat) or LF (Research Diets #D12450J - 10% kcal fat)
diet and given water with or without 0.25% monobutryin for 6 weeks.
Status Completed
Public Release 2/20/2021
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainAnimal Count
Data Analysis
TypeCount
Animals23
Experimental Conditions8
Catalog Items3
Curation Info (# flags)2
Phenotype Assays2
Phenotype Measurements92
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
23
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Monobutyrin
Prophorce SR710 - Gut health and performance enhancer based on monobutyrin
 Vehicle
Vehicle - Control

Experimental Factor: Drug Delivery Route

 Drinking Water
The drug was delivered in the drinking water.

Experimental Factor: Drug Dose Units

 %
% of drug in vehicle

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Research Diets - D08091803B
Custom high fat diet (45% kcal) with cellulose (20% kcal protein; 35% kcal carbohydrates; 45% kcal fat); energy density = 4.7 kcal/g
 Research Diets - D12450J
Rodent Diet with 10% fat, 70% carbohydrate, 20% protein

Experimental Factor: Tissue Source

 colon
colon
 ileum
ileum



No documents found.

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.