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Experiment

Hyperinsulinemic Clamp order #21975 August2016
Summary Data Summary
Investigator Viswambharan, Hema
Description This strain allow to study the role of Type I human Insulin-like growth factor
receptor in mediating Insulin resistance or sensitivity specific to endothelial.

This strain of mice had increased Insulin sensitivity at 12 weeks of age.

We would like to confirm our preliminary findings that this transgene affects
insulin sensitivity

Applicable research area(s): Diabetes, Metabolism, Cardiovascular
Status Completed
Public Release 1/25/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagAnimal Count
Data Analysis
TypeCount
Animals18
Experimental Conditions4
Catalog Items2
Curation Info (# flags)1
Phenotype Assays16
Phenotype Measurements4410
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
9
0
C57BL/6-Hprttm8(Tek-IGF1R*K1003)
0
9
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.



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