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Experiment

Hyperinsulinemic Clamp Order #20705 May 2016
Summary Data Summary
Investigator Kahn, Barbara
Description ChREBP is adipose tissue is down-regulated in insulin resistance and obesity.
However, it isn't known whether this down-regulation is a cause or consequence
of insulin resistance. We will address this by over-expressing ChREBP in adipose
tissue and will determine the putative pathways involved.
Status Completed
Public Release 11/10/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagAnimal CountNomenclature
Data Analysis
TypeCount
Animals36
Experimental Conditions5
Catalog Items2
Curation Info (# flags)2
Phenotype Assays19
Phenotype Measurements10183
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
10
10
0
C57BL/6-Tg(aP2-ChREBP)1Kahn
8
8
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Teklad - 93075
Harlan-Teklad TD.93075 Adjusted Calorie diet (Calories: 21% protein, 55% Fat, 24% Carbohydrate) A diet used to induce obesity. Approximate fatty acid profile (% total fat): 28% saturated, 30% trans, 28% monounsaturated (cis), 14% polyunsaturated...



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