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Tracers in Metabolic Research

Isotope Tracers in Metabolic Research: 3-Part Webinar Series

September - November 2020
Organized by the University of Missouri, Vanderbilt University and the NIDDK

See flyer for details 3 Part Webinar Click here for more information.
Please note each part requires a separate registration (see flyer for details).

Part 1: TUES, SEPT. 15 | 2 - 3 PM CST

"Use of lipid tracers to track fatty acid flux in humans and animal models of NAFLD"
Elizabeth Parks, PhD (University of Missouri School of Medicine)

*Register for Part 1:
Link to seminar video:

Part 2: TUES, OCT. 20 | 2 - 3 PM CST

"Tracing hepatic glucose and glycogen metabolism in metabolic disease"
Owen McGuinness, PhD (Vanderbilt University School of Medicine)

*Register for Part 2:
Link to seminar video:

Part 3: TUES, NOV. 17 | 2 - 3 PM CST

"Central metabolism is a target of Pioglitazone action"
Matt Merritt, PhD (University of Florida College of Medicine)

*Register for Part 3:
Link to seminar video:

*Connection information differs per webinar and will be provided after registration

Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis

13th Annual Course
Postponed until Fall 2021. Exact dates to be determined. Email to be added to course announcements.

A week-long course (with one-on-one mentoring sessions) in the theory and practice of stable and radioactive isotopic tracers for the study of metabolism in human and animal models.

Course Co-Directors: Owen P. McGuinness, PhD, Elizabeth J. Parks, PhD
Sponsored by Mouse Metabolic Phenotyping Centers (MMPC)

Location: Nashville, TN at Homewood Suites by Hilton® Nashville-Vanderbilt

Description: This course provides basic introductory and comprehensive information on performing metabolic studies using tracers labeled with radioactive or stable isotopes in humans, animals and cells. The course is designed for beginners as well as for those with experience who wish to expand their capabilities to more sophisticated problems. The faculty has expertise in a wide variety of applications and methodologies.

Techniques are taught for the investigation of whole body metabolism, for metabolite balance across organs, intracellular flux rates and pathway regulation in humans, animals and cells. Basic aspects of modeling will be considered, as well as specific applications to the study of carbohydrate, fat, protein metabolism and energy balance. Theoretical and practical matters related to sample analysis by mass spectrometry and NMR are discussed, including examples of calculations involved in determining isotopic enrichment and basic kinetic parameters. Attendees will have opportunities to discuss their research projects in one-on-one mentoring sessions with faculty.

Course Logistics (registration, course syllabus, hotel information):

Contact: Eann Malabanan at

Glucose Clamping the Conscious Mouse: A Laboratory Course
UPDATE: Due to the COVID-19, the 2020 course has been postponed until 2021
The Vanderbilt-NIDDK Mouse Metabolic Phenotyping Center (MMPC) presents the 18th semiannual course -
Glucose Clamping the Conscious Mouse: A Laboratory Course
October 2021
Co-Directors: David Wasserman, PhD, Owen McGuinness, PhD, Julio Ayala, PhD, Louise Lantier, PhD

Vanderbilt-NIDDK Mouse Metabolic Phenotyping Center
Location: Vanderbilt University
8455 Medical Research Building IV
Nashville, Tennessee
Overview: A week-long course to familiarize participants with methods, protocols and quantitative tools necessary to perform glucose clamps in the conscious mouse. This course is intended for investigators and staff who wish to make clamping a regular component of their research program.
Visit Vanderbilt-NIDDK Mouse Metabolic Phenotyping Center for more details.



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